High Priority Sites
Il Grande Museo Del Duomo: Includes on-line ticket purchase information. There are 463 steps to the top of the dome. The dome is open from 8:30 to 6:30 Monday to Saturday.
Uffizi: The official web-site is at Uffizi Galleries. See Wikipedia for an overview.
Accademia: The gallery that includes the "David" and several other Michelangelo sculptures. Ticket information is available at Polo Museale Fiorentino.
Other Starred Sites
La Specola: Florence's unusual Museum of Zoology and Natural History. For a description, see Wikipedia. Positive reviews for this museum can be found at TripAdvisor.
Chapel Of The Magi (Cappella dei Magi): Benozzo Gozzoli's fresco "Procession of Magi" (1459) is in the Palazzo Medici-Riccardi. See also Magi Chapel -- Wikipedia, Palazzo Medici Riccardi -- Wikipedia, and the Museums of Florence site. Booking is advisable. The museum is open 9-6 from Thursday to Tuesday.
Brancacci Chapel: Features Masaccio's masterpiece. For an overview, see Wikipedia. See also Museums Of Florence. Reservations are recommended (055 2768558). Open 10 am - 5 pm, Mon., Wed.-Sat.
National Archaeological Museum (Florence): An overview of the museum is provided at Wikipedia.
Boboli Gardens With Vasari Corridor Tour:
Other Possible Sites
Bargello: The Wikipedia site includes basic information. Donatello's "David" is one of the star attractions.
Palazzo Vecchio: Basic information is provided by Wikipedia. Hidden Italy offers a Guided Tour With Giorgio Vasari. It still fulfills its role as the city's civic hall.
Santa Croce: Includes the tombs of Michelangelo, Galileo and Machiavelli.
Sassetti Chapel: Inside the Basilica of Santa Trinita, this chapel is notable for Domenico Ghirlandaio's "Stories of St. Francis."
San Marco -- Wikipedia: Includes a series of frescoes by Fra Angelico. See Convent Of San Marco -- The Museums Of Florence for a fuller sampling of the paintings. The official web-site is at Museum Of San Marco.
Basilica Of Santa Maria Novella: For an overview, see Wikipedia.
Museo Galileo: A small museum dedicated to the famous scientist.
Touring Information
Firenze Musei has information on advance Florence Museum tickets.
Musei Civici Florentini: Information about the city's civic museums.
Transportation
Getting To Florence By Air: Includes information about getting the 4 kilometers from the airport to the historic core.
Useful Websites
Turismo In Toscana: The official Tuscany tourism web-site.
Possible Accommodations
Hotel Bavaria: Located in a former palace in the historic core, this could be a good place for staying upon arrival. Booking options include the hotel site and a possibly cheaper room at Expedia.
Hotel Crocini: Another possible budget option upon arrival. See TripAdvisor for reviews. Booking information is available on Expedia.
A Room With A View/Camera Con Vista: A few minutes from the centre of town. (Via Fratelli Dandolo, 5 piano II -- second floor; +39 3335 737 810)
Characteristic Artist's Apartment: (Via dei Pepi 64; +39 3920 656 520)